Radiology and imaging serve as the eyes of modern medicine, allowing doctors to peer inside the human body without making a single incision. This rapidly evolving field uses technologies like X-rays, MRI scans, and ultrasound to detect diseases, guide treatments, and monitor patient recovery. As new research emerges, these visual tools become increasingly sophisticated, offering deeper insights into conditions ranging from broken bones to complex neurological disorders.

At Gist.Science, we bridge the gap between raw scientific data and public understanding by processing every new preprint in this category from medRxiv. Our team translates these complex studies into both plain-language overviews and detailed technical summaries, ensuring that breakthroughs in medical imaging are accessible to everyone, from students to specialists. Below are the latest papers in radiology and imaging, ready for you to explore.

📄 radiology and imaging

Multi-centre validation of MELD-graph for automated focal cortical dysplasia detection using 7T compared to paired 3T MRI

This multi-centre study demonstrates that while the MELD-graph tool maintains comparable sensitivity for detecting focal cortical dysplasia at 7T MRI as it does at 3T, its specificity is significantly lower, necessitating cautious interpretation and highlighting the benefits of harmonisation despite limited gains from 7T-specific pipeline adaptations.

Kronlage, C., Ripart, M., Piper, R. J., Casella, C., Klodowski, K., Bauer, T., Eriksson, M. H., Bridgen, P., Tisdall, M. (…)2026-10-11
📄 radiology and imaging

Benchmarking open-source automated thigh muscle MRI segmentation algorithms

This study addresses the lack of independent comparisons in the field by benchmarking eight open-source automated thigh muscle MRI segmentation algorithms across diverse datasets, revealing that while domain-specific models generally outperform foundation models, significant performance variations and reduced accuracy on pathological cases highlight critical trade-offs between accuracy, generalizability, and clinical usability.

Moore, C. M., Alper, M.2026-09-22
📄 radiology and imaging

Soft Temporal Scoring Using a Foundation Model: Optimal Frame Selection for Improved ONSD Measurement in Ultrasound Videos

This paper presents a sparsely supervised AI framework that leverages an ultrasound foundation model with Gaussian soft temporal scoring to automatically select optimal frames for ONSD measurement in ultrasound videos, significantly outperforming existing baselines and enabling reliable intracranial pressure assessment in low-resource settings.

Ali, M., Castaneda, L. M., Wu, C., Escamilla-Ocanas, C. E., Hirzallah, M., Brattain, L. J.2026-09-22
📄 radiology and imaging

Association of plasma biomarkers with longitudinal change in age- and Alzheimer's disease-related brain atrophy patterns

In cognitively unimpaired individuals from the Baltimore Longitudinal Study of Aging, plasma p-tau217 demonstrated the strongest association with both subsequent Alzheimer's disease-related dementia and longitudinal changes in AD-specific brain atrophy patterns compared to other plasma biomarkers.

Bilgel, M., Shah, I., Cooper, J., An, Y., Walker, K. A., Ho, S. G., Moghekar, A. R., Yang, Z., Erus, G., Davatzikos, C. (…)2026-09-17
📄 radiology and imaging

Hyperspectral imaging in the emergency department to characterize lower leg edema

This study demonstrates that visible/near-infrared hyperspectral imaging, particularly when analyzed using full-spectrum machine learning algorithms, can accurately and rapidly classify cellulitis, non-cellulitis edema, and healthy lower-leg tissue in emergency department patients across diverse skin pigmentation types.

Kasi, K., May, C., Gallegos, H., Kobayashi, L., Conway, B. R., Pare, J. R.2026-09-16
📄 radiology and imaging

Liver functional radiomics of gadoxetic acid-enhanced magnetic resonance imaging: A proof-of-concept study

This proof-of-concept study identified a set of reproducible and repeatable radiomics features from gadoxetic acid-enhanced MRI that significantly correlate with quantitative liver function indices, establishing a foundation for future liver function-related radiomics research.

Wang, Q., Grigoriadis, A., Gilg, S., Tzortzakakis, A., Sparrelid, E., Brismar, T. B.2026-09-14
📄 radiology and imaging

Diameter measurement of tubular structures on CT angiography, 3D rotational angiography, and 2D digital subtraction angiography against caliper ground truth: A phantom study of surrogates for intracranial vessels.

This phantom study evaluates the accuracy of CTA, 3DRA, and 2D DSA in measuring intracranial vessel diameters against physical ground truth, revealing that while all modalities generally measure within 0.5 mm of true dimensions, they exhibit consistent biases that vary by vessel size, contrast concentration, and detection algorithm, with maximum-gradient edge detection proving superior to FWHM and fixed-HU methods.

Alexander, M., Settecase, F.2026-09-08
📄 radiology and imaging

LDCT-to-SDCT as a Bridge Problem: Single-Step Residual Endpoint Flow Matching for Real-Time Denoising

This paper introduces Residual Endpoint Flow Matching (REFM), a single-step deep learning method that leverages the inherent anatomical similarity between low-dose and standard-dose CT images to achieve real-time, high-quality denoising comparable to iterative diffusion models while drastically reducing computational costs.

dela Sotta, T., Saavedra, J. M., Chang, V., Xavier, A., Henriquez, H., Orellana, Y., Curimil, J.2026-08-31